Kanker Vulva
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Kanker vulva adalah keganasan ginekologi yang jarang terjadi pada wanita (1% dari seluruh keganasan pada wanita). Sekitar 80-90% jenis histopatologi kanker vulva adalah karsinoma sel skuamosa. Faktor risiko terjadinya kanker vulva adalah usia lanjut, adanya lesi prekanker, infeksi HPV, imunodefisiensi, merokok dan lichen sclerosis. Keterlibatan kelenjar getah bening merupakan faktor prognosis terpenting yang dapat menurunkan overall survival. Modalitas terapi pada kanker vulva adalah kombinasi antara operasi, kemoterapi dan radioterapi. Preservasi anatomi dan fungsi organ menjadi menjadi pertimbangan penting dalam menentukan tatalaksana kanker vulva. Pada makalah ini akan dibahas peran radiasi pada kanker vulva.
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Albuquerque K. Part 23 : Vulva Cancer .In: Lu JJ, Brady LW (ed.). Decision Making in Radiation Oncology Vol. 2. Verlag Berlin Heidelberg : Springer. 2011.pp. 703-24.
Montana GS, Kang SK. Chapter 72 : Carcinoma of the Vulva. In :Perez CA, Brady LW (ed.). Perez and Brady's Principles and Practice of Radiation Oncology, 5th Edition. Philadelphia: Lippincott Williams & Wilkins. 2007.pp. 3272-83.
Netter, F.M. Bab 12. Alat Genitalia Wanita. Dalam : Netter FM. Atlas Anatomi Manusia. Edisi 5. Philadelphia: Elsevier Saunders. 2010.
Kang HK, Yun JH, Son YM, Roh JY, Lee JR. Photodynamic Therapy for Bowen’s Disease. Ann Dermatol 2014: 24 (2) pp. 241-5
Netter, F.M. Gross Anatomy of the Vulva. Available at http://netterimages.com/female-perineum-and-externalgenitalia-pudendum-or-vulvar-labeled-anatomy-atlas-5egeneral-anatomy-frank-h-netter-49347.html
Koh WJ, Greer BE, Abu-Rustum NR, Apte SM, Campos SM, Cho KR, et al. Vulvar Cancer. 2016. National Comprehensive Cancer Network. Available at http:// www.nccn.org
American Cancer Society. Vulvar Cancer. 2016. Atlanta:
American Cancer Society. Diunduh dari : https:// www.cancer.org/cancer/vulvar-cancer.html.
Luesly DM, Tristram A, Ganesan R, Barton DPJ, Stianou JJ, Gallagher C, et al. Guideline for the Diagnosis and Management of Vulvar Carcinoma.London: British Gynecological cancer society. 2014. pp. 1-30.
Russel AH, Van der Zee AG. Chapter 58 : Vulvar Carcinoma.In : Gunderson LL, Tepper JE. Clinical Radiation Oncology. Third Edition. Philadelphia: Elsevier Saunders.2012.pp. 1241-65.
Stehman FB, Bundy BN, Thomas G, Varia M, Okagaki T, Robert J, et al. Groin dissection versus groin radiation in carcinoma of the vulva: a GOG study. Int J Radiat Oncol Biol Phys. 1992: 24. pp. 389–96
Kunos C, Simpkins F, Gibbons H. Radiation therapy compared with pelvic node resection for node-positive vulvar cancer. Obstet Gynecol 2009: 114. pp 537–46
Van der Zee AG, Oonk MH, De Hullu JA, Sluiter WJ. Sentinel node dissection is safe in the treatment of earlystage vulvar cancer. J Clin Oncol 2008: 26. pp.884–889
Mundt AJ, Yashar C, Mell LK. , Part 23:Vulvar Cancer. In: Lu JJ (ed.).Target volume delineation and Field Setup, A Practical Guide for Conformal and Intensity-Modulated Radiation Therapy. Verlag Berlin Heidelberg : Springer.2013. pp. 207-11.
Surveillance, Epidemiology and End Results (SEER). Program stat fact sheet on vulva cancer. 2013. Available at http://seer.cancer.gov/statfacts/html/vulva.html
Tabaa ZM, Gonzales J, Sznurkowski JJ, Weaver AL, Mariani A, Cliby WA. Impact of the New FIGO 2009 Staging Classification for Vulvar Cancer on Prognosis and Stage Distribution. Gynecologic Oncology 2012: 127. pp. 147-52.
Thaker NG, Klopp AH, Jhingran A, Frumovits M, Iyer RB, Eifel PJ. Survival Outcomes for Patients with Stage IVB Vulvar Cancer with Grossy Positive Lymph Nodes: Time to Reconsidered the FIGO Staging System? Gynecol Oncol. 2015. 136(2).pp. 269-73
DOI: https://doi.org/10.32532/jori.v8i1.57 <
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